NIA funds the Columbia University Alzheimer’s Disease Research Center (ADRC) to conduct research on improving diagnosis and care and to search for effective treatments. Part of this mission is to share resources with other investigators including pathological, clinical, neuroimaging, genetic information, and biospecimens.
Any investigator interested in utilizing such resources must complete this web-based request form:
All investigators must have an active IRB approval for studies involving human tissues. The Resource Committee, whose goal is to aid investigators in accessing and utilizing the resources and in fostering new research, will review the request for completeness and accuracy. All fields of the request must be completed, incomplete request will delay processing.
Acceptance of ADRC data and/or materials obligates the recipient to cite/reference the NIA grants supporting this project. The ADRC is supported by the National Institutes of Health, through Grant Number P30AG066462.
The following citation must be used: "Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health under Award Number P30AG066462. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."
In addition to resources available directly from the ADRC database, the ADRC has committed to facilitating access to resources available from three other major Columbia University projects with a focus on Alzheimer’s disease: NIA-LOAD, WHICAP and EFIGA.
The National Institute on Aging Genetics Initiative for Late-Onset Alzheimer's Disease (NIA-LOAD) is a study of families with two or more siblings with the late-onset form of Alzheimer's disease and a cohort of unrelated, non-demented controls similar in age and ethnic background. It is widely considered the most utilized AD genetics dataset in the world, with samples, clinical and genotyping data, and preliminary analyses available to qualified investigators worldwide.
The Washington-Heights/Inwood Columbia Aging Project (WHICAP) is a community-based longitudinal study, recruiting elderly subjects from Northern Manhattan. Cohorts were established in 1992, 1999, and 2009. Subjects are evaluated every two years.
Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA) is a study based on a cohort of Caribbean Hispanics with Late-Onset Alzheimer’s Disease recruited from clinics in the Dominican Republic and New York.
We encourage all researchers to review the multitude of resources available and provided by the NIA/NIH. Please take the time to review the recently updated NIH website Alzheimer's resource page.