The Symposium will showcase transformative, fundamental research in Human Genetics for a broad audience of biologists and biomedical researchers. To this end, we bring together an interdisciplinary set of speakers (below) to present their work on the causes and consequences of genetic and environmental perturbations of human phenotypes.
EVENT PROGRAM CAN BE FOUND HERE.
October 10, 2024
9:00¬–9:10 a.m. Molly Przeworski, PhD: Introductory Remarks
9:10–¬9:50 a.m. Inigo Martincorena, PhD: Somatic Mutation and Clonal Selection in Normal Tissues
9:50–10:30 a.m. Sarah Aitken, PhD: Disentangling Strand Interactions in DNA Damage and Repair
10:30–11:00 a.m. Break
11:00–11:40 a.m. Anjali Hinch, PhD: How Our Genomic Landscape Is Reshaped in the Making of Eggs and Sperm
11:40 a.m.–12:20 p.m. Jennifer Phillips-Cremins, PhD: Dissecting the 3D Genome’s Structure-Function Relationship in the Mammalian Brain
12:20–1:30 p.m. Lunch
1:30–2:10 p.m. Vijay G. Sankaran, MD, PhD: Genetic Influences on Human Hematopoiesis
2:10–2:50 p.m. Adrianna San Roman, PhD: Genomic Contributions to Sex Differences in Human Biology
2:50–3:20 p.m. Break
3:20–4:00 p.m. Yun Song, PhD: Learning Complex Functional Constraints in Proteins and Non-coding DNA
4:00–4:15 p.m. Provost Angela Olinto, PhD
4:15–5:00 p.m. Reception
October 11, 2024 - UPDATED
9:30–9:40 a.m. Christine K. Garcia, MD, PhD: Introductory Remarks
9:40–10:20 a.m. Jonathan Pritchard, PhD: Integrating Genetic Association Data with Cellular Perturbations to Study the Molecular Pathways of Human Trait Variation
10:20–11:00 a.m. Break
11:00–11:40 a.m. Michel Georges, DVM: eQTL Matching IBD Risk Loci: Paucity or Plethora?
11:40 a.m.–12:20 p.m. Nasa Sinnott-Armstrong, PhD: Complex Dynamics Underpin Gene-Environment Interactions
12:20–1:30 p.m. Lunch
1:30–2:10 p.m. Miriam Udler, MD, PhD: Process-Specific Polygenic Scores for Insights into Disease Mechanisms
2:10–2:50 p.m. Gil McVean, PhD: Longitudinal Modeling of Human Disease Comorbidities and the Implications for Our Understanding of Risk and Pathology
2:50-–3:20 p.m. Break
3:20–4:00 p.m. Nancy Cox, PhD: How the Genetic Component to Laboratory Measurements in Medicine Can Degrade Outcomes and Add to Health Inequities: What Should We Do When the Genetics Adds Noise, Not Signal?
4:00–4:40 p.m. Simon Myers, PhD: Why Does Genomic Trait Prediction Translate Poorly across Human Ancestries?
4:40–4:50 p.m. Molly Przeworski, PhD: Closing Remarks
