Our Publications


Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model

Samantha M Rossano, Aubrey Sperling Johnson, Anna Smith, Galen Ziaggi, Andrew Roetman, Diana Guzman, Amarachukwu Okafor, Julia Klein, Zeljko Tomljanovic, Yaakov Stern, Adam M Brickman, Seonjoo Lee, William C Kreisl, Patrick Lao
Alzheimer's & Dementia (2024)

Microglial Activation, but Not Tau Pathology, Is Independently Associated With Amyloid Positivity and Memory Impairment

DOI: 10.1016/j.neurobiolaging.2019.09.019
Zou, James, Sha Tao, Aubrey Sperling Johnson, Zeljko Tomljanovic, Krista Polly, Julia Klein, Qolamreza R. Razlighi et al. 
Neurobiology of Aging 85 (2020): 11-21.

Untangling the Relationship Between Microglia and Tau in Alzheimer's Disease

DOI: 10.1016/j.tins.2021.10.002
Rossano, Samantha M., and William Charles Kreisl.
Trends in Neurosciences 44, no. 12 (2021): 927-929.

Olfactory Impairment Is Related to Tau Pathology and Neuroinflammation in Alzheimer's Disease

DOI: 10.3233/JAD-201149
Klein, Julia, Xinyu Yan, Aubrey Sperling Johnson, Zeljko Tomljanovic, James Zou, Krista Polly, Lawrence S. Honig et al. "Olfactory impairment is related to tau pathology and neuroinflammation in Alzheimer’s disease." 
Journal of Alzheimer's Disease 80, no. 3 (2021): 1051-1065.

Deep Learning Improves Utility of Tau PET in the Study of Alzheimer's Disease

DOI: 10.1002/dad2.12264
Zou, James, David Park, Aubrey Sperling Johnson, Zeljko Tomljanovic, Davangere P. Devanand, Jose Luchsinger, Adam M. Brickman, William Charles Kreisl, and Frank Provenzano.
Alzheimer's & Dementia 17 (2021): e054310.

Patterns of Tau Pathology Identified With 18 F-MK-6240 PET Imaging

DOI: 10.1002/alz.12384
Kreisl, William Charles, Patrick J. Lao, Aubrey Sperling Johnson, Zeljko Tomljanovic, Julia Klein, Krista Polly, Benjamin Maas et al.
Alzheimer's & Dementia 18, no. 2 (2022): 272-282.


Posters & Abstracts


Validating noninvasive techniques for [11C]ER176 PET quantification in controls and Alzheimer’s disease patients

Samantha M. Rossano, Daniel Talmasov, Aubrey S. Johnson, Anna C. Smith, Diana S. Guzmán, Amarachukwu Okafor,William C. Kreisl, Philip L. De Jager, Patrick J. Lao

Discovering Correlates of Off-Target 18F-MK6240 Signal in Community-Dwelling Adults

Aubrey S. Johnson, Amarachukwu Okafor, James Zou, Anna Smith, Diana S. Guzmán, William C. Kreisl, Adam M. Brickman, José A. Luchsinger, Patrick J. Lao

Elevated Tau burden in Amygdala and Hippocampus amongst older participants with psychosis

Aubrey S. Johnson, Galen Ziaggi, Hannah M. Houlihan, Anna C. Smith, Diana S. Guzmán, Amarachukwu Okafor, Edward D. Huey, William C. Kreisl, Daniel Talmasov, Patrick J. Lao

Tau burden is associated with sleep disordered breathing in adults with Down syndrome

Anna Smith, Sigan Hartley, David T. Plante, Aubrey S. Johnson, Diana S. Guzmán, Amarachukwu Okafor, Samantha Rossano, Dana Tudorascu, Adam M. Brickman, Bradley T. Christian, Ozioma Okonkwo, Beau Ances, Annie Cohen, Benjamin L. Handen, Patrick Lao

Moderate alcohol use, total brain volume, and white matter hyperintensities among racially and ethnically diverse middle-aged adults

Diana S. Guzmán, Miguel Arce Rentería, Justina F. Avila, Indira C. Turney, Samantha M. Rossano, Aubrey Sperling Johnson, Anna C. Smith, Amarachukwu Okafor, Clarissa Morales, Yian Gu, Jennifer J. Manly, Adam M. Brickman, Patrick J. Lao

Psychosis and tau burden in older adults

Aubrey S. Johnson*, Galen Ziaggi*, Anna Smith, Edward D. Huey,William C. Kreisl, Daniel Talmasov, Patrick Lao
*These authors contributed equally

Differential properties of Early vs. Late 18F-Florbetaben imaging acquisition time frames

Aubrey S. Johnson, Anna C. Smith, Zeljko Tomljanovic, Galen Ziaggi, Andrew E. Roetman, Julia Klein, Richard Keegan, Lawrence S Honig, William Charles Kreisl

Abstract: DOI:10.1002/alz.067766