The Center will focus its research programs on activities related to research on the underlying mechanisms of neurodegenerative diseases, specifically Alzheimer's Disease, and including but not limited to Parkinson's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Motor Neuron Disease, and other neurological conditions resulting from neurodegeneration. 

Upon the completion of Columbia’s new research building, Ludwig researchers will move to this new wet-lab research facility, located on the corner of 167th Street and Audubon Avenue. Currently in the design phase, the building will house Ludwig Center faculty and dozens of other researchers working collaboratively in areas of basic and translational research and precision medicine, using such tools as genomics, stem cells, animal models, and computational biology to inform advances in patient care. This space will support strong ideas exchange and communication among researchers and will also provide the enhanced scientific tools and infrastructure needed to achieve the Center’s work.

A cornerstone of the center will be pilot awards designed to advance and accelerate innovative new research projects, with seed funding for especially promising areas of investigation. Investigators with projects directed toward delivering actionable biomarkers or novel therapies, particularly those based upon a valid target a translational/commercialization trajectory, are encouraged to apply. For more information about our pilot grant program and request for application process, please visit:

Ludwig Pilot Grant Program in Neurodegeneration