Clinical Trials
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Principal Investigator:
Jason Brant Carmel, MD, PhDThe Weinberg Family Cerebral Palsy Center's (WFCPC) research team maintains a cerebral palsy (CP) patient registry of more than 1,000 enrolled patients. This registry contains information collected from children and adults with CP. The goal of the registry is to help us learn more about CP and neuromuscular diseases, to understand the quality of life of patients with these diseases, and to study different treatment and surgical options. The registry allows our researchers to capture a more complete picture than ever of the full scope of patients living with CP and to investigate long-term... -
Principal Investigator:
Sloane Heller, MDThe purpose of this study is to understand how liver disease affects thinking and memory, both before and after transplant. Participants will take a cognitive test, which will be a series of tasks and questions similar to a video game, at home on their own computers, tablets, or phones. This will take approximately 45 minutes, and participants will do this once a year for 3 years. We will assess how thinking and memory changes over time and in response to transplant. -
Principal Investigator:
Rebecca Straus Farber, MDWe need your help today to gather information about the experience of patients with autoimmune diseases of the central nervous system (multiple sclerosis (MS), neuromyelitis optica (NMO), and anti-MOG associated disease (MOGAD)) in regards to COVID-19 vaccines. Because individuals with MS, NMO, and MOGAD were not included in the COVID-19 vaccine trials, we want to learn more about the experience of individuals with these autoimmune diseases and the vaccine. Because many patients with central nervous system autoimmune disease also take medications that affect the immune system, we want to find... -
Principal Investigator:
Philip L. De Jager, MD, PHDThe Snapshot study aims to understand brain and spinal cord aging in healthy individuals and individuals with multiple sclerosis (MS). We aim to identify new tools that will help us to achieve successful brain aging in the general population and in people with an underlying autoimmune disease. A critical aspect of this study is that we are looking for individuals who are willing to donate their brain and spinal cord when they pass away; this will enable the investigators to understand which molecules in the brain made someone more or less likely to age successfully. The brains will be housed... -
Principal Investigator:
Sheng-Han Kuo, MDParticipate in learning more about Impulsivity and Compulsivity in Spinocerebellar ataxia (SCA). Why? By investigating individuals with SCA, we will gain valuable insights into the specific mechanisms through which the cerebellum participates in cognitive processes. Who? Healthy adults over the age of 18, who would like to participate as controls. What? Participation involves one clinic visit for 3-4 Hours, involving cognitive baseline measurements, an electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) recording during which a decision-making two-step task will be... -
Principal Investigator:
Jason Brant Carmel, MD, PhDA key part of the CP definition is that it is a non-progressive brain injury. However, as people with CP age, their function often deteriorates. This study seeks to determine whether changes in the brain structure may result in function changes, as they do in other types of brain injuries. -
Principal Investigator:
Philip L. De Jager, MD, PHDWe're testing a new type of MRI scanner that's smaller and portable - like a mobile MRI unit. This makes it easier to provide brain scans to people who have difficulty traveling to hospitals or live far from medical centers. We'll be studying people with multiple sclerosis (MS) and similar brain conditions. Our goal is to learn how well this portable scanner can measure brain changes and how these changes relate to memory and thinking abilities. By validating this technology, we hope to make MRI scanning more accessible to everyone while advancing our understanding of conditions like MS. The... -
Principal Investigator:
Philip L. De Jager, MD, PHDThe Snapshot study aims to understand brain and spinal cord aging in healthy individuals and individuals with multiple sclerosis (MS). We aim to identify new tools that will help us to achieve successful brain aging in the general population and in people with an underlying autoimmune disease. A critical aspect of this study is that we are looking for individuals who are willing to donate their brain and spinal cord when they pass away; this will enable the investigators to understand which molecules in the brain made someone more or less likely to age successfully. The brains will be housed... -
Principal Investigator:
Philip L. De Jager, MD, PHDMS Genetics aims to better understand the genetic component of demyelinating diseases by doing genetic testing on blood samples of participants. This study involves a one-time blood draw and completion of questionnaires spread out over a couple of years in hopes to better understand the genes that makes one predisposed to Multiple Sclerosis and various other demyelinating diseases. -
Principal Investigator:
Sheng-Han Kuo, MDWhy: To investigate cerebellar physiological activity during motor tasks in Essential Tremor. Who: Adults over the age of 18, diagnosed with Essential Tremor. What: Participation involves one clinic visit for 2-3 Hours, involving EEG measurements from the scalp (non-invasive), wearable sensors on the hand, feet and back to measure postural movement. This will be followed by non-invasive brain stimulation during resting-state and during movement tasks. Cost to me: There is no cost involved for participating in the study. You will receive $50 after completion of the study. Location: 710 W 168th...