Andrew F. Teich, MD, PhD

Pathology - Anatomic
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Laboratory website: Teich Lab

Academic Appointments

  • Associate Professor of Pathology and Cell Biology (in Neurology)

Administrative Titles

  • Director of the New York Brain Bank

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Male

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Credentials & Experience

Education & Training

  • Columbia University College of Physicians and Surgeons
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Board Certifications

  • Neuropathology
  • Anatomic Pathology

Honors & Awards

  • 2016 Paul B. Beeson Emerging Leaders Career Development Award in Aging, NIH-NIA
  • 2014 Margaret M. Cahn Research Award, Alzheimer’s Association
  • 2011 Louis V. Gerstner, Jr. Scholar Award, Louis V. Gerstner, Jr. Scholar Foundation/Columbia University


Our laboratory uses human brain tissue specimens and human cell-derived model systems to study the pathogenesis of Alzheimer’s disease (AD) and identify viable therapeutic targets.  I am also the Director of the New York Brain Bank, and we are using tissue specimens from this repository to better understand the heterogeneity of AD pathology and how this may impact clinical presentation.  We use a broad range of computational and molecular techniques, and collaborate extensively with other PIs at CUIMC.

Welcome to Teich Lab!


Selected Publications

  • Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF. ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. Journal of Neuroscience 2024 Jan 17;44(3):e2324222023. doi: 10.1523/JNEUROSCI.2324-22.2023.
  • Huang, W., A.M. Bartosch, H. Xiao, X. Flowers, S. Leskinen, Z. Tomljanovic, G. Iodice, D. Boyett, E. Spinazzi, V. Menon, R.A. McGovern, G.M. McKhann, and A.F. Teich, An Immune Response characterizes early Alzheimer’s disease pathology and subjective cognitive impairment in hydrocephalus biopsies. Nature Communications, 2021 Sep 27;12(1):5659. doi: 10.1038/s41467-021-25902-y.
  • Zeljko Tomljanovic, Mitesh Patel, William Shin, Andrea Califano, Andrew F. Teich. ZCCHC17 is a master regulator of synaptic gene expression in Alzheimer's Disease. Bioinformatics, 2018 Feb 1;34(3):367-371.
  • A. F. Teich, Sakurai M., Patel M., Holman C., Saeed F., Fiorito J., Arancio O. PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease. Journal of Alzheimer's Disease, 2016 9;52(1): 295-302.
  • Teich AF, Patel M, Arancio O. A Reliable Way to Detect Endogenous Murine β-Amyloid. PLoSOne. (2013) 8(2):e55647.