Adam M. Brickman, PhD

  • Professor of Neuropsychology (in Neurology and in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H. Sergievsky Center)
Profile Headshot

Overview

Academic Appointments

  • Professor of Neuropsychology (in Neurology and in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H. Sergievsky Center)

Gender

  • Male

Credentials & Experience

Education & Training

  • PhD, Psychology and Neuropsychology, Graduate School of the City University of New York
  • Neuroscience and Psychology, Oberlin College
  • Internship: Brown Medical School
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Committees, Societies, Councils

  • 2014: Fellow of the American Psychological Association (APA)

Research

Dr. Brickman’s work focuses on understanding the vascular contributions to cognitive aging and Alzheimer’s disease in genetic, clinical, and community-based contexts. His work integrates neuroimaging and fluid biomarkers into observational studies, basic neuroscience, and epidemiological approaches. He is also interested in understanding sources of racial and ethnic disparity in Alzheimer’s disease, developing interventions for cognitive aging, and designing neuropsychological instruments to assess cognition in older adults.

Research Interests

  • Aging
  • Alzheimer's Disease
  • Cognitive Aging
  • Dementia
  • Down Syndrome
  • Functional and Structural Neuroimaging
  • Magnetic Resonance Imaging (MRI)
  • Neuroimaging
  • Neurology
  • Neuromorphology
  • Neuropsychiatric Disorders
  • Neuropsychology
  • Schizophrenia

Selected Publications

  1. Liou JJ, Lou J, Flores-Aguilar L, Nakagiri J, Yong W, Hom CL, Doran EW, Totoiu MO, Lott I, Mapstone M, Keator DB, Brickman AM, Wright ST, Nelson B, Lai F, Xicota L, Dang LT, Li J, Santini T, Mettenburg JM, Ikonomovic MD, Kofler J, Ibrahim T, Head E; Alzheimer Biomarker Consortium ? Down Syndrome. A neuropathology case report of a woman with Down syndrome who remained cognitively stable: Implications for resilience to neuropathology. Alzheimers Dement. 2025 Feb;21(2):e14479. doi: 10.1002/alz.14479. Epub 2025 Jan 27. PMID: 39868632; PMCID: PMC11851131.
  2. Kennedy JT, Wisch JK, Dincer A, Roman J, Gordon BA, Handen B, Benzinger TLS, Head E, Mapstone M, Christian BT, Tudorascu DL, Laymon CL, Hartley SL, Lao P, Brickman AM, Zaman SH, Ances BM; ABC?DS and DIAN Consortia. Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome. Alzheimers Dement. 2025 Feb;21(2):e14519. doi: 10.1002/alz.14519. Epub 2025 Jan 14. PMID: 39807622; PMCID: PMC11848172.
  3. Lee JH, Scambray KA, Morris EP, Sol K, Palms JD, Zaheed AB, Martinez MN, Schupf N, Manly JJ, Brickman AM, Zahodne LB. Marital status, brain health, and cognitive reserve among diverse older adults. J Int Neuropsychol Soc. 2024 Nov 26:1-10. doi: 10.1017/S1355617724000638. Epub ahead of print. PMID: 39587737.
  4. Rosas HD, Mercaldo ND, Hasimoglu Y, Petersen M, Lewis LR, Lai F, Powell D, Dhungana A, Demir A, Keater D, Yassa M, Brickman AM, O'Bryant S. Association of plasma neurofilament light chain with microstructural white matter changes in Down syndrome. Alzheimers Dement (Amst). 2024 Nov 22;16(4):e70023. doi: 10.1002/dad2.70023. PMID: 39583646; PMCID: PMC11582681.
  5. Lee AJ, Sanchez D, Reyes-Dumeyer D, Brickman AM, Lantigua RA, Vardarajan BN, Mayeux R. Reliability and Validity of Self-Reported Vascular Risk Factors: Hypertension, Diabetes, and Heart Disease, in a Multi-Ethnic Community Based Study of Aging and Dementia. J Alzheimers Dis. 2023;95(1):275-285. doi: 10.3233/JAD-230374. PMID: 37483004; PMCID: PMC10578288.
  6. Calcetas AT, Thomas KR, Edmonds EC, Holmqvist SL, Edwards L, Bordyug M, Delano-Wood L, Brickman AM, Bondi MW, Bangen KJ, For The Alzheimer's Disease Neuroimaging Initiative. Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment. Neurobiol Aging. 2022 Oct;118:1-8. doi: 10.1016/j.neurobiolaging.2022.06.002. Epub 2022 Jun 16. PMID: 35809348; PMCID: PMC9838569.