Photo of a brain in a lab

New Approach to Alzheimer's Treatment

July 5, 2022

Columbia’s Scott Small, MD, has been one of many Alzheimer’s researchers who say it’s time to abandon amyloid-based therapies.

“In the 90s, the idea that amyloid is the trigger of Alzheimer’s was extremely exciting, and there was a sense that we were on the cusp of curing this devastating, horrible disease,” he says. “It was the right idea based on the available evidence, but the evidence has changed.”

That evidence–which Small and other Columbia researchers played pivotal roles in developing over the past 20 years–is pointing to an alternative theory of Alzheimer’s. [read more]

Source: CUIMC Newsroom